National Brain Injury Rescue & Rehabilitation (NBIRR) Study

Brain Injuries Can Linger for Years

Some Wounds Never Heal

If you've ever had a concussion

If you were ever exposed to an explosion or blast

If you've been diagnosed with Chronic Traumatic Brain Injury (TBI)/Post-Traumatic Stress Disorder (PTSD)

You may be eligible to participate in a study, which Fox Valley Wellness Center/Midwest Hyperbarics is honored to participate in, to find out if oxygen under pressure can heal wounds in the brain.

Call Center for the National Brain Injury Rescue & Rehabilitation Clinical Trial

(800) 288-9328

Hyperbarics Oxygen Therapy & NBIRR Study


Hyperbaric oxygen has a number of potential effects on the body including:
  • Angiogenesis – stimulates growth of capillaries in hypoxic tissue to improve wound healing
  • Hyperoxygenation – high levels of oxygen can help with the repair of cellular function
  • Osteogenesis – HBOT can stimulate the production of new bone cells in compromised bones
  • Microbiological – high levels of oxygen help eliminate anaerobic bacteria
  • Immune Stimulation – increased phagocytosis and natural killer cells
  • Decreased Inflammation – decrease in TNF alpha, cytokines and cyclo-oxygenase
  • Vasoconstriction – oxygen causes the constriction of blood vessels which can reduce oedema
  • Bubble Reduction – increased pressure decreases nitrogen bubbles in decompression illness
  • Tissue Repair – increase in stem cell production may help in tissue repair/regeneration

    The mainstream and hospital-based uses for HBOT include the following:

  • Lyme disease
  • Cancer
  • Air or gas embolism
  • Carbon monoxide poisoning
  • Acute traumatic ischemia 
  • Exceptional blood loss 
  • Cyanide poisoning 
  • Decompression illness ("bends")
  • Clostridial myonecrosis 
  • Radiation proctitis 
  • Some non-healing wounds
  • Gas gangrene
  • Necrotizing infections
  • Some cases of osteomyelitis
  • Radiation-induced tissue damage
  • Compromised grafts and skin flaps
  • Burns
  • Compartment syndrome
  • There are a growing number of extra conditions that may respond to increased oxygen levels. For many of these the level of scientific proof is limited or anecdotal. These include:hyperbaric chamber

  • Cerebral palsy 
  • Stroke 
  • Multiple sclerosis 
  • Head injuries and concussion
  • Mycoplasma + Lyme disease
  • Before and after surgery
  • Chronic fatigue
  • Sports injuries
  • Autism
  • Migraine + cluster headaches
  • Idiopathic sudden deafness
  • Systemic fungal infection
  • Parkinson's disease
  • Trigeminal neuralgia
  • Raynaud's phenomenon
  • Vascular disease
  • Crohn's disease (especially if fistula)
  • Fibromyalgia
  • Decreased immune function
  • Venomous bites
  • Retinal artery occlusion
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